Treated with breast conversing surgery and sentinel lymph node biopsy or axillary lymph node dissection
Pathologically confirmed invasive breast cancer
A pathological T1-2N0M0 tumor
Tumor bed is labeled with Titanium clips
Negative surgical margins
Written informed consent.
You may not be if
KPS\<70
Treated with neoadjuvant chemotherapy
Sentinel lymph nodes only containing isolated tumour cells (\<0.2 mm)
With severe comorbidity
Previous breast cancer or other malignant tumor history
Previous radiotherapy for breast or thorax
Medical contraindication for radiotherapy
Pregnant or nursing
Clareo Health | Hypofractionated Whole-breast Irradiation With Simultaneously Integrated Boost For Early-Stage Breast Cancer After Breast-conserving Surgery