Endocrine Therapy With or Without Cryoablation for Stage IV Prostate Cancer

Exclusion Criteria

• •History of malignant disease
• •History of coronary artery disease
• •Uncontrolled infection
• •Other concurrent severe or uncontrolled medical disease that could compromise participation in the study (i.e., uncontrolled diabetes mellitus, uncontrolled cardiac disease, uncontrolled hypertension, congestive cardiac failure, ventricular arrhythmias, active ischemic heart disease, myocardial infarction within the past six months, chronic liver or renal disease, and active upper gastrointestinal tract ulceration)
• •Psychological, familial, sociological, or geographical condition potentially hampering compliance with the study treatment and follow-up schedule