Observational Analysis of T Cell Responses to SPIREs for Multiple Allergens in Subjects With Allergy in North America

Exclusion Criteria

• •1. Clinically relevant history of alcohol or drug abuse.
• •2. Use of any oral or parenteral (except low dose inhaled) corticosteroids within 2 months prior to the visit or any other immunosuppressive therapy within 3 months prior to the visit.
• •3. Vaccination/ inoculation within the 6 weeks prior to the first visit.
• •4. A history of any significant disease or disorder (e.g. autoimmune, cardiovascular, pulmonary, gastrointestinal, liver, renal, neurological, musculoskeletal, endocrine, metabolic, neoplastic/malignant, psychiatric, major physical impairment, severe atopic dermatitis).
• •5. Subjects who have taken an investigational drug within 6 weeks prior to the visit or are currently participating in any other clinical study.
• •6. Recent blood donation of an amount of \>100 mL.
• •7. Immunotherapy within the last 5 years to any of the allergens for which a subject would otherwise be eligible on the basis of clinical history and skin prick test result.