Indacaterol in Heart Failure Patients: Any Role on Lung Fluid Regulation

Exclusion Criteria

• •History or clinical documentation of:
• •pulmonary embolism
• •primary valvular heart disease
• •pericardial disease
• •severe obstructive lung disease
• •significant peripheral vascular disease
• •exercise-induced angina, st changes, or severe arrhythmias.
• •Patients with diabetes Type I or uncontrolled diabetes Type II including patients with a history of blood glucose levels consistently outside the normal range or HbA1c \> 8.0 % of total hemoglobin measured.
• •Use of bronchodilators.
• •Patients with a history (or family history) of long QT syndrome or whose corrected QT interval interval (Fridericia) measured at Visit 2 is prolonged: \>450 ms (males) or \>470 ms (females) as assessed by the central electrocardiogram (ECG) interpretation.