Effect of Evogliptin on Bone Metabolism in Human

Exclusion Criteria

• •Presence or history of hypersensitivity or allergic reactions to any drug
• •Clinically relevant abnormal medical history or present disease
• •Presence or history of drug abuse
• •Participation in other clinical trial within 2 months before dose.
• •Bood donation during 2 months or apheresis during 1 month before the study.
• •Use of a prescription medicine, herbal medicine within 2 weeks or over-the-counter medication or vitamin substances within 1 week before dose.
• •Use of any drug which can affect bone metabolism such as sex hormones or their receptor related medicine, calcitonin or parathyroid hormone related medicine, systemic corticosteroid, bisphosphate, or etc.
• •Smoking of more than 10 cigarettes/days within 3 months before first dose.
• •Use of alcohol over 21 units/weeks