Gerhard Garhofer, MD

CONTACT

Doreen Schmidl, MD, PhD

CONTACT

Lead Sponsor

Medical University of Vienna

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

•Men and women aged over 18 years
•Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
•Normal ophthalmic findings, ametropia \< 6 Dpt.
•Men and women aged over 18 years
•DES patients will be included based on three questions:
•* (1) "Have you ever been diagnosed (by a clinician) as having dry eye syndrome?"
•* (2) "Do you currently use artificial tear eyedrops or gel?"
•* (3) "For the past three months or longer, have you had dry eyes? (This is described as a foreign body sensation with itching and burning, sandy feeling, not related to allergy)."
•Normal ophthalmic findings except dry eye syndrome

•Participation in a clinical trial in the 3 weeks preceding the study
•Symptoms of a clinically relevant illness in the 3 weeks before the first study day
•Wearing of contact lenses
•Intake of dietary supplements in the 3 months preceding the study
•History of glaucoma
•Treatment with corticosteroids in the 4 weeks preceding the study to topical treatment with any ophthalmic drug in the 4 weeks preceding the study (topical lubricants for patients with DES are allowed)
•Ocular infection or clinically significant inflammation
•Ocular surgery in the 3 months preceding the study
•Sjögren's syndrome
•Stevens-Johnson syndrome
•Pregnancy, planned pregnancy or lactating