Lead Sponsor

Mamatha Pasnoor, MD

Collaborators

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•CIDP diagnosed according to the European Federation of Neurological Societies/Peripheral Nerve Society (EFNS/PNS) criteria 2010
•Age \> 18 years
•Able to give written informed consent
•Patient's signs and symptoms should not be better explained by another disease process
•Patients can be on prednisone as long as there has been no dose change for 4 weeks from baseline
•Patients can be on following drugs as long as there has been no change for 60 days from baseline visit including azathioprine, cyclosporine, cyclophosphamide, mycophenolate mofetil, intravenous immunoglobulin (IVIg) or other immunosuppressive drugs
•INCAT score greater than or equal to 2

•Presence of any other causes of polyneuropathy or multifocal motor neuropathy, which in the opinion of the investigator is the major contributor to the numbness and weakness.
•Other neurologic or orthopedic condition causing weakness
•Treatment with plasma exchange (PLEX) within the last 30 days from baseline
•Participation in another trial within the last 30 days from baseline or two ½ life of the drug being studied.
•Latent tuberculosis or active infection
•Contraindication per Acthar® Gel prescribing information scleroderma, osteoporosis, systemic fungal infections, ocular herpes simplex, recent surgery, history or presence of peptic ulcer, congestive heart failure, uncontrolled hypertension, primary adrenocortical insufficiency, or adrenal cortical hyperfunction.
•History of prior sensitivity to Acthar® Gel or other porcine products
•Previous or present Infection with hepatitis C and hepatitis B
•Pregnancy or nursing mothers.
•Female subjects of childbearing potential either not using, or not willing to use, a medically reliable method of contraception for the entire duration of the study, or not sexually abstinent for the entire duration of the study, or not surgically sterile.