Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hospices Civils de Lyon
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient suffering from drug-resistant focal epilepsy
Age ≥ 18 years
Patient for whom a video-EEG monitoring of their seizures was scheduled as part of a pre-surgical assessment
For women of childbearing age, a method of contraception considered effective by the investigator
Patient who have given their written informed consent
Patient accepting an interview with a psychologist and to be refered to a psychiatrist in the event that mood disorders were detected on mood scores and considered severe by the investigator and / or psychologist, leading to require psychiatric care or immediate antidepressant treatment
Patient with a social security number
You may not be if
Age \< 18 years
* Patient under legal protection
* Pregnant or breastfeeding women
* Hypersensitivity to fluoxetine or its excipients
* History of other serious side effects related to an earlier prescription of fluoxetine;
* Current suicidal ideation or history of suicide attempt
* Manic episode
* Disruption of liver enzymes considered material by the investigator using the following criteria:
transaminases (ALT and AST)\> 2N alkaline phosphatase (ALP)\> 2N gamma glutamyl transpeptidase (GGT)\> 5N (performed as part of routine monitoring of epileptic patients on antiepileptic treatment. Patients often exhibit changed deemed clinically insignificant due to the enzyme-inducing effect of these drugs)
Renal failure with creatinine clearance \<30 ml / min
Acute heart disease
Antidepressant treatment
Other prohibited treatment (see detailed list in protocol).
Clareo Health | Efficacy of Fluoxetine Against Seizure-induced Central Apneas
