Tranexamic Acid in Chronic Subdural Hematomas

Exclusion Criteria

• •Acute subdural hematoma with no chronic component;
• •Active thrombotic, thromboembolic or atheroembolic disease, including deep venous thrombosis within the last six months, cerebral thrombosis within the last six months, symptomatic carotid stenosis who did not undergo surgery or stroke within the last year;
• •Past history of unprovoked deep venous thrombosis or idiopathic pulmonary embolism;
• •Known hereditary thrombophilia, including Factor V Leiden, Antithrombin III mutation, Protein C deficiency, Protein S deficiency;
• •Atrial fibrillation (unless under successful rhythm control therapy);
• •Metallic heart valve;
• •Vascular stenting procedure within the last year;
• •Cardiac or vascular surgical procedure within the last 6 months, including endarterectomy, bypass or angioplasty;
• •Ongoing investigation for suspected malignancy;
• •Confirmed active malignancy;
• •Concomitant hormone therapy for malignancy;
• •Concomitant hormone contraceptive pill;
• •Macroscopic hematuria;
• •Known or suspected tranexamic acid allergy;
• •Pregnancy or breastfeeding;
• •Concomitant use of anticoagulant medication;
• •Any concern from the attending physician.