A crossover trial to establish an optimized tDCS protocol will be accomplished. Anodal and cathodal tDCS will be applied over the primary motor cortex (C3 - active and contralateral supra-orbital region - reference) and visual cortex (Oz - active and Cz - reference). Dual tDCS (anodal and cathodal - optimized protocol) will be applied on C3 - active and Oz - active.
Electrical cortical activity will be assessed on 14 migraineurs through: (i) MEP; (ii) MT; (iii) SICI; (iv) ICF; (v) PT and (vi) visual evoked-potential (VEP-habituation). An interval of 48hs between sessions will be taken. The order of the sessions will be randomized and counterbalanced among volunteers by site www.randomization.com.
Age
18–55
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ages: 18-55 years
Gender: Both
Presented diagnostic of episodic migraine with or without aura or probably migraine with or without aura according to the criteria for diagnosis of ICHD-III
Disease duration of at least 12 months
Without preventive medication for at least 6 months prior to initiation of treatment
You may not be if
Pregnant women;
Pacemaker;
History of seizures;
Metallic implants in the head;
Patients with clinical evidence of brain injuries;
