Effect of Exercise Training in Patients With Pulmonary Hypertension

Inclusion Criteria

• •WHO functional class II-IV
• •PH diagnosed by right heart catheter showing:
• •Baseline mean pulmonary arterial pressure (mPAP) ≥ 25 mmHg
• •Baseline pulmonary vascular resistance (PVR) \> 240 dyn x s x cm-5
• •Baseline pulmonary capillary wedge pressure (PCWP) ≤ 15 mm Hg
• •Patients receiving maximal PH therapy including intensified treatment with diuretics and who have been stable for 2 months before entering the study
• •PH target therapy should not be expected to change during the entire 15-week study period
• •Negative pregnancy test (β-HCG) at the start of the trial
• •Able to understand and willing to sign the Informed Consent Form