Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle

Inclusion Criteria

• •1. Healthy, male and non-pregnant female subjects, 18 years of age or older.
• •2. A diagnosis of papulopustular rosacea with ≥30 inflammatory facial lesions at Baseline. Subjects must have no more than 2 nodular lesions, at Baseline.
• •3. Subjects with the presence of telangiectasia at Baseline.
• •4. Subjects with an erythema score of at least 2 on the Investigator Assessment of Erythema scale at Baseline.
• •5. Subjects with severe rosacea on the Investigators Global Assessment scale at Baseline.