Lead Sponsor

University Hospital, Caen

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patient with heart failure on optimal medical therapy and targeted for cardiac resynchronization therapy according to current recommendations;
•Age over 18 years
•Clinically stable (without hospitalization for heart failure in the last month)
•Sinus rhythm
•Social security insurance
•Signed consent form

•Recent history (less than 21 days) of acute coronary syndrome or unstable angina;
•Recent history (less than 1 month) of acute heart failure;
•Right bundle branch block;
•Irregular heart rate;
•Double-chamber cardiac pacemaker
•Patients previously implanted with a single-chamber cardioverter-defibrillator must have at least 99 percent of unstimulated QRS.
•Countraindication to dobutamine therapy;
•Valvular heart disease, congenital heart disease, hypertrophic cardiomyopathy;
•Significant Ventricular arrhythmias;
•Hypertension (upper than 160/100 mmHg);
•Pregnant, breastfeeding or guardianship

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