Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain

Exclusion Criteria

• •History of alcohol or substance abuse within the last 6 months as self-reported
• •Severe depression (with a score of \>30 in the Beck Depression Inventory)\*
• •History of seizures during the last two years or diagnosis of epilepsy
• •History of neurological or psychiatric illness
• •Unstable medical conditions such as uncontrolled diabetes mellitus, uncompensated cardiac pathology, heart failure, kidney insufficiency or chronic obstructive pulmonary disease, acute thrombosis
• •History of head injury resulting in more than a momentary loss of consciousness during the last two years
• •History of unexplained fainting spells or loss of consciousness as self-reported during the last two years
• •Contraindication to tPCS or tDCS
• •Metallic brain implants
• •Implanted brain electronic medical devices
• •Pregnancy
• •Use of neuropsychotropic drugs within the past two weeks as self reported
• •Part 2: 18 patients with Chronic Visceral Pain will take part in this experiment. All subjects must meet the following criteria:
• •History of alcohol or substance abuse within the last 6 months as self-reported
• •Severe depression (with a score of \>30 in the Beck Depression Inventory)\*
• •Epilepsy
• •Unstable medical conditions such as uncontrolled diabetes mellitus, uncompensated cardiac pathology, heart failure, kidney insufficiency or chronic obstructive pulmonary disease, acute thrombosis
• •History of head injury resulting in more than a momentary loss of consciousness during the last two years
• •History of unexplained fainting spells or loss of consciousness as self-reported during the last two years
• •Contraindication to tPCS or tDCS
• •Metallic brain implants
• •Implanted brain electronic medical devices
• •Pregnancy or trying to become pregnant during the next month
• •Use of carbamazepine oxcarbazepine, phenytoin, pramipexole (Mirapex), or cavergoline (Dostinex) within the past 6 months as self-reported