Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA

Exclusion Criteria

• •Administration of other analgesics or sedatives, if not administered in stable dosages for at least 14 days or if not used for premedication and surgery
• •Administration of hydromorphone or morphine in the period between screening and surgery
• •Severe hepatic or renal impairment in medical history
• •BMI\>= 35 ASA\>= 4