Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Ingeborg Stalmans, Phd
CONTACT
Sien Boons
CONTACT
Lead
Universitaire Ziekenhuizen KU Leuven
With
* A prospective, randomized, investigator-masked, crossover comparison; * Ocular hypertension or glaucoma (XFG or POAG) patients and who consent to participate will be enrolled in this study * Patients will be scheduled for a screening visit IOP assessment (IOP measurements at 08:30, 12:30 and 16:30 (±1 hour). * Patients who are on therapy at the screening visit and who consent to participate will undergo a washout period for 4 weeks (depending on therapy) before the baseline visit; * Patient can under the washout period be given brinzolamide (Azopt) if needed, Azopt should then be discontinued 5 days before baseline visit; * After the screening visit (and after wash-outperiod for treated patients) patients will be scheduled to undergo a baseline visit IOP assessment (IOP measurements at 08:30, 12:30 and 16:30 (± 1 hour with a minimum of 3 hours between readings) and will then be randomized for Period 1 to receive either BIMMD drops once in the evening (20:30) or TUDPF drops once in the evening (20:30) for 3 month * After 3 month, patients will be switched for Period 2, to the opposite treatment (e.g. switched to either BIMMD or TUDPF) to be dosed in the evening; * After another 3 months they will undergo the final evaluation of IOP levels and of tolerability; * Intermediate safety visits may be scheduled at the discretion of the investigator.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
