Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation

Exclusion Criteria

• •Prior history of mechanical circulatory support;
• •Body weight \< 110 lbs;
• •Pre-existing hemolytic, bleeding, or immunologic disorders prior to LVAD implantation;
• •Severe aortic stenosis;
• •Renal failure requiring dialysis;
• •Hepatic dysfunction resulting in severe coagulopathies;
• •Recent serious infection;
• •Current need for prolonged ventilatory support;
• •Prior organ transplantation;
• •Blood transfusion within 14 days of the first planned study blood draw;
• •Concomitant immunosuppressant or chemotherapeutic agents;
• •Pregnant women;
• •Decisionally challenged or prisoners;
• •Unwilling to provide written informed consent