Effectiveness of Two Self Assessment Tools: KIOS-Bipolar or eMoods

This Phase II study has the specific aim of evaluation of KIOS-Bipolar in a randomized, open 52 week effectiveness study of 120 bipolar subjects in current treatment at three socioeconomically diverse academic health science centers. Concurrent with this clinical effectiveness study, the research team, funded by the same NIH grant,will refine prototype software and integrate data security and establish quality standards into the KIOS-Bipolar system. The clinical trial will: Assess sensitivity of K-B assessed improvement or worsening by comparison with assessment by BISS-Self and BISS-42.