Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Southern California Institute for Research and Education
Age
20–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
1. participants must satisfy diagnostic criteria for Obstructive sleep apnea.
2. evidence of pulmonary hypertension disease base upon one or more of the following: RVSP \> 35 mmHg OR Mean PA pressure\>25 mmHg, RVSP \< 35 mmHg OR Mean PA pressure \< 25 mmHg (as control).
3. age greater than or equal to 20 years.
4. no significant alcohol use (7 or fewer drinks per week).
You may not be if
1. peripheral vascular disease
2. liver disease
3. Pregnancy. A serum pregnancy test must be performed and negative in all women of child bearing potential within 2 weeks prior to enrollment.
4. Any medical or psychosocial condition that, in the opinion of the investigator, could jeopardize the subject's participation, and compliance with the study criteria.
5. hemolytic anemia
6. inflammatory disease
7. active infection,
8. on therapy for OSA,
9. on chronic steroid treatment,
10. younger than 20 years of age,
11. patients with left heart failure (systolic or diastolic),
12. patients are on pulmonary hypertension medications including sildenafil,
13. active smokers,
14. COPD and asthma,
15. active infection or inflammatory disease
16. collagen vascular disease.
Clareo Health | Role of Heme-oxygenase (HO) and Nitric Oxide (NO) Pathway in Patients With Obstructive Sleep Apnea (OSA) and Pulmonary Hypertension (PH)
