Before the anesthetic induction every included patient will follow these protocol:
* Standard monitoring (ECG Electrocardiogram, SpO2 Pulsed oxygen saturation)
* Insertion of radial arterial line and periferic IV line under local anesthesia,
* Insertion of a internal jugular central line and Swan Ganz catheter under local anesthesia
* Preoxygenation in 100% oxygen for 10 min
* Further preoxygenation with a mixture of 100% oxygen associated with the iNO in a dose of 1,2 L / mn.
* Anesthesia induction and initiation of mechanical ventilation.
* Progressive decrease of iNO dose and stop of iNO administration.