Efficacy and Safety of GLPG1205 in Subjects With Active Ulcerative Colitis

Exclusion Criteria

• •History of sensitivity to any component of the study drug, or a history of drug or other allergy
• •Any concurrent illness, condition, disability, or clinically significant abnormality that, in the investigator's opinion, represents a safety risk for the subject's participation, may affect the interpretation of data, or may prevent the subject from safely completing the assessments
• •History of significant psychological, neurologic, hepatic, renal, endocrine, cardiovascular, GI (other than UC), pulmonary, or metabolic disease
• •History of active infections requiring intravenous antibiotics within the past 4 weeks prior to screening.
• •History of malignancy within the past 5 years; presence or history of intestinal malignancy
• •History of bowel surgery within 6 months prior to screening; history of colon resection with \< 30 cm of the colon remaining
• •Suspicion of Crohn's disease, indeterminate colitis, microscopic colitis, ischemic colitis, diverticular disease-associated colitis, or radiation-induced colitis
• •Subject who has received non-permitted UC therapies within specified timeframes, depending on the medication, as stated in the protocol
• •Subject who is pregnant or lactating