The Leaky Lung Test

Exclusion Criteria

• •1. \>5 pack year history of tobacco use or active smoking.
• •2. Other chronic or active lung diseases (e.g. COPD, pulmonary fibrosis, lung cancer)
• •3. History of significant renal insufficiency of liver disease
• •4. Asthma subjects with severe disease according to NAEPP guidelines (e.g. severe ongoing symptoms despite high-dose inhaled or oral glucocorticoids)
• •5. Asthma subjects with a baseline FEV1\<65% predicted
• •6. Asthma subjects unwilling or unable to withhold medications prior to testing
• •7. Pregnant women.