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Lead
University of Colorado, Denver
The purpose of this research project is to determine the effects of omega-3 fatty acid supplementation on intraocular pressure (IOP) as well as the signs and symptoms of dry eye. We hypothesize that dietary omega-3 fatty acid supplementation will be associated with a significant change in intraocular pressure compared to baseline measurements prior to beginning supplementation. We further hypothesize that omega-3 fatty acid supplementation will be associated with a significant increase in tear production and volume as well as a significant change in patients' subjective complaints of dry eye.
Age
40–89
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of Ocular Hypertension or Open Angle Glaucoma of mild to moderate severity, with or without previously diagnosed dry eye syndrome, who are currently on monotherapy with a prostaglandin analog.
Age 40-89 of either gender, of any race/ethnicity
You may not be if
Females who are currently pregnant or planning to become pregnant during the study period
Age \<40 years old
Diagnosis of any other form of glaucoma other than open-angle
Patients with known hypersensitivity (i.e., anaphylactic reaction) to omega-3 fatty acids or any of its components
Patients with cirrhosis or with known liver disease
Patients with diagnosed celiac disease
Patients with a hypersensitivity to fish or shellfish
Patients with paroxysmal or persistent atrial fibrillation
Patients who are currently using medical or recreational marijuana
Patients currently on any anticoagulation therapy including warfarin, dabigatran, apixaban, rivaroxaban, clopidogrel, cilostazol, dipyridamole, prasugrel, ticlopidine, ticagrelor
Patients currently on Lovaza, an omega- 3 fatty acid supplement requiring a prescription
Patients with any recent ocular surgery or laser treatment within 3 months
Clareo Health | The Effect of Omega-3 Fatty Acid Supplementation on Intraocular Pressure & Ocular Surface
