Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Fondren Orthopedic Group L.L.P.
With
InGeneron, Inc.
This research study will be a randomized study in which patients volunteer participate. "Randomized" means the patients who received the new treatment are chosen at random, similar to flipping a coin. Several factors have been identified as possible sources of thigh pain after surgery: use of a tourniquet around the thigh to control bleeding during surgery; use of an intramedullary rod during surgery or quadriceps muscle strain. Participants will be randomized into surgical groups that use/do not use a tourniquet and use/do not use intramedullary rod during surgery. A subset of participants in all surgical groups will have a MRI to look for quadriceps muscle strain.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Subjects undergoing total knee arthroplasty for osteoarthritis
Adult patients (age 18 years or older)
Written informed consent
Ability to speak, read and write English or Spanish
You may not be if
Inability to speak, read and write English or Spanish
Evidence of malignant disorder/neoplasm in past 60 months
Contraindication for removal of infrapatellar fat pad
History of smoking and not committed to give up
Chronic skin conditions
Connective, metabolic or skin disease
Evidence of active infection
Pregnancy or lactating for female subjects
Current corticosteroid use
Immunosuppressive medication
Renal failure (creatine \> 1.8 mg/dL)
Hepatic failure (AST, ALT \> 2x normal values; bilirubin \> 2 mg/dL)
Inflammatory joint diseases of the knee that indicate additional, conflating therapies
Joint infection within the past 6 months
No prisoners or mentally disabled persons
No Workers' Compensation cases
Clareo Health | Thigh Pain After Total Knee Arthroplasty (TKA)
