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Lymphedema Study for Arm or Leg Lymphedema | Clinical Trials | Clareo Health

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COMPLETEDPhase 4NCT02257970

Lymphedema Study for Arm or Leg Lymphedema

This study compares the effectiveness of a study drug versus placebo in the treatment of lymphedema.

Lead sponsor: Stanford University•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Stanford University

Part 1 is feasibility, exploratory, open-label study of ketoprofen, to document effects. Part 2, is open-label trial of ketoprofen to document histological response. Part 3 is double-blind randomized trial of receive placebo or ketoprofen to evaluate safety and efficacy. We will try to determine how the study drug affects the body tissue by obtaining tissue biopsies (small pieces of skin from the arm or leg) before treatment and after treatment.

Age

18 - 90 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•a history of lymphedema of one or more limbs (unilateral or bilateral), with a duration of \> 6 months.

Exclusion Criteria

•Patients with active cancer, infection or bleeding tendency will be excluded.
•We will also exclude patients with medical contraindications to NSAIDs, including history of allergies, know gastrointestinal intolerance, or other serious systemic illness (e.g., renal failure, hepatic dysfunction, congestive heart failure, neurological or psychological impairment) that would impair the patients' ability to participate.
•Minors (\<18 years of age) \*\>90 years of age

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 27, 2022Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment117

Start dateMar 2009

Last updatedOct 27, 2022

Condition

Locations shown

Stanford University

Stanford, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 27, 2022Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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