Pre-Workout on Exercise Performance and Cognition

Exclusion Criteria

• •1. Subject has any of the following medical conditions:
• •* active heart disease
• •* uncontrolled high blood pressure (≥ 140/90 mmHg)
• •* renal or hepatic impairment/disease
• •* Type I or II diabetes
• •* bipolar disorder
• •* pulmonary disease (including current asthma)
• •* Parkinson's disease
• •* Seizure disorder
• •* unstable thyroid disease
• •* immune disorder (such as HIV/AIDS)
• •* active psychiatric disorders (including anxiety disorders)
• •* bleeding disorders
• •* gastrointestinal ulcer disease
• •* any medical condition deemed exclusionary by the Principal Investigator (PI)
• •2. Subject has any orthopedic problem(s) or history of musculoskeletal injury(ies) which make(s) resistance weight training contraindicated.
• •3. Subject has a history of cancer (except localized skin cancer without metastases) within 5 years prior to screening.
• •4. No prescription or chronic medication use allowed without PI discretion.
• •5. Subject is currently taking and unwilling to refrain from taking any over-the-counter stimulant medications/supplements (see section 2.6.2); seven-day washout required for study inclusion.
• •6. Subject is currently taking and unwilling to refrain from taking any over-the-counter allergy or asthma medication containing pseudoephedrine or ephedrine (see section 2.6.2); seven-day washout required for study inclusion.
• •7. Subject has an allergy to milk and phenylalanine, or any of the ingredients in the test product (see section 3.2.1).
• •8. Subject reports sensitivity to caffeine and/or beta-alanine.
• •9. Subject reports being a regular caffeine consumer defined as consuming \> 600 mg of caffeine per day.
• •10. Subject exhibits evidence of hepatic or renal dysfunction as evidenced by ALT, AST, AP being ≥ two times the upper limit of normal or serum creatinine value ≥ 2.0 mg/dl or other clinically significant abnormal clinical laboratory value per PI discretion.
• •11. Subject has a clinically relevant abnormality as defined by the PI or interpreting physician with respect to the ECG.
• •12. Subject has a QTcB interval \> 450 msec.
• •13. Subject has a history of drug or alcohol abuse in the past 12 months.
• •14. Subject has any condition or abnormality that, in the opinion of the investigator, would compromise the safety of the subject or the quality of the study data.
• •15. Subject has taken an investigational product within 30 days of the first exercise test visit (visit 2).