Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
McMaster University
With
Hamilton Health Sciences Corporation
Age
18–75
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
female patients 18-75 years of age
undergoing a unilateral or bilateral mastectomy or partial-mastectomy (breast conserving surgery), for prophylactic (e.g. family history or BRCA gene mutation) or belief of isolated (non-metastatic) cancerous lesions
receiving a general anesthetic
You may not be if
previous breast surgery within six months of index surgery
undergoing a DIEP (Deep Inferior Epigastric Perforator) flap procedure
patient has chronic pain or a chronic pain syndrome for which they have taken 4 or more daily medications (i.e. opioids, anti-convulsants, anti-spasmodic, anti-depressants, anti-inflammatories) or routine pain intervention (i.e. nerve blocks) during the past 3 months
documented hypersensitivity or allergy to pregabalin, gabapentin, or lidocaine
history of ventricular tachycardia, ventricular fibrillation, or atrioventricular block ≥ type II
history of congestive heart failure
renal insufficiency with creatinine \> 120 µmol/L
known or previously documented cirrhosis
pregnant
unable to swallow study medications
patient's surgeon believes patient is inappropriate for inclusion in trial
unlikely to comply with follow-up (e.g. no fixed address, plans to move out of town)
language difficulties that would impede valid completion of questionnaires
patient requires gabapentin or pregabalin for a medical condition or has been taking gabapentin or pregabalin daily during the past 1 week
Clareo Health | Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
