BioEnergetics and Metabolomics in Cystic Fibrosis

Exclusion Criteria

• •current pregnancy
• •unwilling or unable to discontinue enteral tube feeds for one night before the study visit, if applicable
• •most recent FEV1% \<40%
• •drug (recreational or prescription) or alcohol abuse
• •pacemaker or any electronic implantable device
• •unable to give informed consent
• •Healthy volunteers
• •current pregnancy
• •current active malignant neoplasm or history of malignancy (other than localized basal cell cancer of the skin) during the previous 5 years
• •current respiratory disease including asthma, chronic obstructive pulmonary disorder, or emphysema
• •current chronic autoimmune or pro-inflammatory disease
• •history of tuberculosis, HIV, or other chronic infection
• •previous diagnosis of type 1 or type 2 diabetes with active treatment with insulin or other glucose lowering medication
• •advanced (≥ stage 3) renal disease
• •body mass index (BMI) ≥ 30 kg/m2
• •acute illness (such as a viral infection) within the past 2 weeks
• •current use of any prescription medications that would indicate presence of an acute or chronic medical condition that may influence study results
• •drug (recreational or prescription) or alcohol abuse
• •weight instability (± 10% body weight within the last 6 months) or current participation in weight loss or weight gain program
• •inability to provide informed consent.