Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Cancer Advances Inc.
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients with histologically confirmed colorectal carcinoma for whom no other anti-cancer treatment was anticipated during the three month period of study.
Patients taking a proton pump inhibitor at a fixed daily dose which had remained unchanged for at least six weeks preceding screening and was not anticipated to change during the study.
Proton pump inhibitor compliance of \~70% (to be measured between screening and baseline (week 0)).
Male or female patients from 18 to 65 years of age.
Patients with a life expectancy of over three months.
World Health Organisation (WHO) Performance Status of 0 to 1.
Written informed consent given.
You may not be if
Patients in receipt of histamine H2-receptor (H2 receptor) antagonists or any other antacid therapy, other than a proton pump inhibitor at a stable dose.
Patients with any other factor likely to alter intra-gastric acidity e.g. previous gastric surgery, including vagotomy or anatomically abnormal upper gastrointestinal tract.
History of other malignant disease within the previous five years, except non- melanomatous skin cancer or in situ carcinoma of the uterine cervix.
Previous use within the last four weeks, concomitant use or anticipated use in the period of the study of radiotherapy or chemotherapy.
Concomitant use of immunosuppressants, including systemic (i .e. oral or injected) corticosteroids.
Females who were pregnant, planning to become pregnant or lactating. Women, who in the opinion of the investigator were of child bearing potential, were to have a negative pregnancy test before study drug administration.
Patients taking part in another study involving an investigational or licensed drug or device in the three months preceding enrolment or during the study.
Previous G 17DT treatment.
Haematological indicators:
Haemoglobin \<10.0 g/dL White blood cell count \<4.0 x 109/L Platelets \< 100 x 1 09/L
