Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
New York Medical College
Age
1–21
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Recurrent or refractory solid tumors. This may include, but is not limited to, osteosarcoma, chondrosarcoma, Ewing's sarcoma, Wilm's Tumor, medulloblastoma, neuroblastoma, hepatoblastoma, rhabdomyosarcoma, retinoblastoma, and primitive neuroectodermal tumors. Histologic proof malignancy must have been available at the time of initial diagnosis.
Age: 1-21
Patients must have received standard first-line chemotherapy or other appropriate standard first line therapy for their malignancy.
Patients must have radiologic or histologic evidence of recurrence
Patients must have fully recovered from the toxic effects of the prior chemotherapy and must have an ANC \>1000/μL and a platelet count \>100,000/μL
Performance status \> 60 from Lansky (age 1 to 16) or Karnofsky (age \> 16)
Adequate hepatic and renal function (AST, ALT, bilirubin and creatinine \< 2.5 x upper normal limit).
Parent or guardian able to provide informed consent and have signed an approved consent form that conforms to federal and institutional guidelines.
You may not be if
Patients who, in the investigator's opinion, have extensive bone marrow involvement with tumor
Presence of significant active infection or uncontrolled bleeding
Pre-existing liver disease , other than liver metastasis
Use of recreational drugs within the prior month
Known history of positive hepatitis B surface antigens or HCV antibodies
Known history of positive test for HIV antibodies
Patients receiving any form of anticoagulant therapy
Presence of a known bleeding disorder or coagulation abnormality
Treatment with any other investigational agent, or participation in another clinical trial within 28 days prior to study entry
Pregnant or breast-feeding patients
Patient with childbearing potential not using adequate contraception
Hemorrhage risk that requires maintenance of platelet counts at 50,000 or higher.
Psychiatric or neurologic conditions that could compromise patient safety or compliance, or interfere with the ability of the patient or family to give proper informed consent.
Clareo Health | ODSH + ICE Chemotherapy in Pediatric Solid Tumors
