Prior intolerance to transpyloric feeds

History of surgical anti-reflux procedure

Congenital heart disease (not including patent ductus arterioles and hemodynamically insignificant ventricular septal defect or atrial septal defect)

Structural abnormalities of the upper airway, lungs, or chest wall

Other congenital malformations or syndromes that adversely affect life expectancy or cardio-pulmonary development

Parent, guardian, or subject who, in the opinion of the investigators, are unlikely to participate for the duration of the study

Transpyloric Feeding in Severe Bronchopulmonary Dysplasia