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Keep this study
Lead
Federation of Breast Diseases Societies
This registry trial evaluating resection of the primary breast tumor in women presenting with de novo stage IV breast cancer with bone metastasis only. Previous reports of carefully selected patients presenting with stage IV breast cancer suggest that surgery on the primary tumor may result in improved survival, but this remains unproven. The early results of our ongoing trial MF07-01 trial (a phase III randomized controlled trial of breast cancer women with distant metastases at presentation who receive loco-regional treatment for intact primary tumor compared with those who do not receive such treatment) showed that patients with bone metastasis only have a trend toward improved survival with initial surgery. Our goal is to test if primary surgery improves overall survival in bone only metastasis.
Age
20–80
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Primary breast tumor amenable for complete surgical resection
Patients in good physical condition for receiving protocol driven locoregional and systemic treatment
Patients eligible for sentinel lymph node (SLN) biopsy and receiving radiotherapy.
You may not be if
Primary tumor not amenable for complete resection (such as tumor extending to neighboring tissues; T4a,c or inflammatory breast cancer; T4d)
Primary tumor with extended infection, bleeding, or necrosis
Patients with poor physical condition which prevents the patient from receiving protocol driven locoregional and systemic treatment
Synchronous primary cancer at the contralateral breast
Previous diagnosis of other cancers (excluding basal cell skin cancer
Squamous cell skin cancer
Cervical intraepithelial neoplasia)
Clinically involved contralateral axillary nodes
Patients not suitable for adequate follow-up
Failure to give informed consent
Clareo Health | Bone Metastasis and Surgery in Breast Cancer
