Lead Sponsor

Beth Israel Deaconess Medical Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Adult patient 18 \> years old
•Chronic pain without clear organic etiology after full evaluation by primary care physician or subspecialist
•Pain persistent for a minimum of 3 days a week for the past three months prior to enrollment

•Patients \< 18 years of age
•Diagnosed organic disease as cause of pain, such as but not limited to malignancy, neurologic disorder (i.e., amyotrophic lateral sclerosis)
•Patients with a diagnosis of significant psychiatric co-morbidities such as schizophrenia and bi-polar disorder. Mild to moderate depression and anxiety will not be considered as exclusions
•Pregnancy
•Severe depression or recent suicide attempt