Known secondary cause of hypertension

Uncontrolled blood pressure (≥ 180x110mmHg)

Unsuitable anatomy of renal arteries, renal stenosis or previous treatment with balloon or stent

Advanced renal insufficiency (estimated glomerular filtration rate (GFR) \< 30 ml/min/1.73 square meters)

Diabetes Mellitus type 1

Acute coronary syndrome or a cerebrovascular accident in the last 6 months

Known other cause of respiratory dysfunction

Previous LV systolic dysfunction (LVEF \< 50%)

Restrictive cardiomyopathy or Hypertrophic cardiomyopathy

Significant valvar dysfunction

Atrial flutter or atrial fibrillation

Use of the oral anticoagulants

Drug and Alcohol dependence

Renal Denervation in Patients With Heart Failure With Normal LV Ejection Fraction