Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure.

Exclusion Criteria

• •Lack of desire to participate
• •In the treatment of OSA
• •Malignant disease
• •Abuse of drugs or alcohol
• •Pregnant and breastfeeding
• •Incompensated heart failure
• •Atrial fibrillation
• •Liver disease (Alanine aminotransferase (ALT)\> 200)
• •Severe chronic obstructive pulmonary disease (COPD) (Forced expiratory volume in 1 second \<50% predicted)
• •eGFR \<60 ml/min/1.73 m2
• •Blood pressure difference between the right and left arm\> 10/10 mmHg
• •Group 2 - Healthy subjects
• •Arterial hypertension, ambulatory blood pressure\> 130 mmHg systolic and / or 80 mmHg diastolic.
• •* a history or clinical signs of cardial, pulmonary, hepato, renal, endocrine, cerebral or neoplastic disorders
• •* Alcohol abuse, ie. \> 14 drinks / week for women and\> 21/uge for men
• •* Substance abuse
• •* Medical treatment apart from oral contraceptives
• •* Smoking
• •* Pregnancy or breastfeeding
• •* Lack of desire to participate
• •* Clinically significant, discrepant results of blood or urine sample at inclusion study (B-hemoglobin and B-White blood cell count, p-sodium, p-potassium, p-creatinine, p-ALT, p-bilirubin , p-Alkaline phosphatase, p-cholesterol, p-albumin or b-glucose and urine for hematuria, albuminuria or glucosuria)
• •* Clinically significant variations in the electrocardiogram
• •* Blood Donation for the past month preceding the day on the first attempt sequence
• •* Blood pressure difference between the right and left arm\> 10/10 mmHg.