Sung Kyun Kim, MD

CONTACT

Lead Sponsor

Seoul National University Hospital

Age

20 - 74 years

Sex

ALL

Healthy Volunteers

No

•1. with informed consent
•2. 20 \<= age \< 75 years
•3. diagnosed as hypertension 6 months (or 3 visits) prior to enrollment, taking anti-hypertensive drugs over 3 months
•4. all-cause chronic kidney disease patients with 15 \<= estimated GFR \< 90
•5. no change of anti-hypertensive drugs within 2 weeks and good compliance

•1. changed prescription according to ambulatory blood pressure monitoring (ABPM) regularly
•2. had acute kidney injury/hospitalization
•3. had a proteinuria of \> 6 g/day (spot urine protein to creatinine ratio \> 6.0 g/g Cr)
•4. had end stage renal disease (ESRD) with dialysis and/or were a kidney recipient
•5. had diseases, such as uncontrolled arrhythmia, uncontrolled bronchial asthma/chronic obstructive pulmonary disease, or primary endocrinologic diseases except diabetes mellitus
•6. were pregnant/lactating women
•7. were night shift workers.