A Phase I Study Evaluating Safety, Tolerability, PK and PD of BL-8040 for Stem Cell Mobilization in Healthy Volunteers

Exclusion Criteria

• •History of clinically significant disease
• •Any illness within the 4 weeks prior to the screening examination
• •Any history of alcohol and/or drug of abuse addiction and/or active / past (up to 2 years before screening) nicotine consumption
• •Clinically relevant deviation from normal in the physical examination and vital signs at screening or baseline
• •Clinically relevant laboratory abnormalities identified at screening or baseline
• •Positive tests at screening for HIV I \& II, hepatitis B and/or hepatitis C in both parts or positive tests for Syphilis, HTLV I \& II and Nucleic Acid Test (NAT) for HIV and HBV
• •Positive test for urine drugs of abuse or by anamnesis (Barbiturates, Benzodiazepines, Amphetamines, Opiates, Cocaine, Cannabinoids, Methadone, Phencyclidine, and Tricyclic Antidepressants) and/or positive alcohol blood test
• •Subjects who have lost or donated in excess of 400 mL of blood within 3 months prior to Day 1 of the study