Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Circassia Limited
With
Adiga Life Sciences, Inc.
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female, aged 18-65 years.
Asthma treated by inhaled SABA or inhaled SABA plus low-medium dose ICS in 6 weeks prior to randomisation.
A reliable history consistent with moderate to severe rhinoconjunctivitis on exposure to ragweed for at least the previous two ragweed seasons.
Positive skin prick test to ragweed
Ragweed-specific Immunoglobulin E (IgE) ≥ 0.35 kU/L.
You may not be if
History of life-threatening asthma.
Uncontrolled asthma according to GINA
FEV1 of \< 70 % of predicted, regardless of the cause.
Administration of adrenaline (epinephrine) is contraindicated (e.g. subjects with acute or chronic symptomatic coronary heart disease or severe hypertension).
History of severe drug allergy or anaphylactic reaction to food.
A history of any significant disease or disorder (e.g. immune system, pulmonary, cardiovascular, gastrointestinal, liver, renal, neurological, musculoskeletal, endocrine, metabolic, malignant, psychiatric, major physical impairment, history of alcohol or drug abuse)
Clareo Health | Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma
