Smoking.

Pregnancy/lactation.

Severe medical illness/chronic disease/ or gastrointestinal pathology (ulcers, irritable bowel syndrome, ulcerative colitis, Crohn disease etc.).

Previous gastrointestinal surgery

Recent use of antibiotics (within 1-month prior to the study)

Suspected hypersensitivity to pomegranate or any of its components

Consumption of nutraceuticals, botanical extracts or other vitamin supplements or taking medication.

Regular consumption of ellagitannin-containing foodstuffs (walnuts, pomegranate, strawberries, raspberries, oak-aged red wine) (after filling a food-frequency questionnaire).

Intake of ellagitannins-containing foodstuffs the week before the pharmacokinetic intervention.

Pharmacokinetics and Bioavailability of Pomegranate Phenolics and Urolithins in Healthy Subjects.

What this study is about