Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
NYU Langone Health
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
For Patients with post-traumatic stress disorder (PTSD)
1. Age 18-55 years old
2. Currently diagnosed with PTSD and symptomatic with a Clinician-Administered PTSD Scale (CAPS) score \> 50
1. Age 18-55 years old
2. No personal or first-degree family history of any Axis I diagnosis
1. . Age 18-55 years old;
2. . No personal or first-degree family history of any Axis I diagnosis;
3. . Has a lifetime history of trauma.
You may not be if
1. any primary Axis I disorder other than PTSD (e.g. psychosis)
2. medical or neurological illnesses likely to affect physiology or anatomy, i.e. uncontrolled hypertension, cardiovascular disorders
3. a history of drug (including benzodiazepines (BZD)) dependence (Diagnostic and Statistical Manual (DSM) IV criteria) within 1 year of the study and lasting longer than 2 years, except for alcohol dependence
4. current pregnancy (as documented by pregnancy testing at screening or on the day of PET imaging study)
5. current breast feeding
6. nicotine dependence
7. suicidal ideation or behavior
9. Human immunodeficiency virus (HIV) (due to possible neuropsychiatric effects)
10. Hepatitis B or C (due to possible neuropsychiatric effects)
11. use of opioid medications within 2 weeks of the positron emission tomography (PET) study
12. having an abnormality in the 12-lead electrocardiogram (ECG) that, in the opinion of the investigator, increases the risks associated with participation in the study
13. seriously claustrophobic
14. blood donation within 8 weeks prior to the study
15. positive alcohol breathalyzer test
16. Abnormal thyroid test indicated by thyroid stimulating hormone (TSH) \< .15 mlU/L and/or thyroxine (T4) \> 18 mcg/dL
17. Glucose \> 200 mg/dL on two separate days
For Healthy Subjects
1. . any history or current primary Axis I disorder ;
2. . medical or neurological illnesses likely to affect physiology or anatomy, i.e. uncontrolled hypertension, cardiovascular disorders;
3. . a history of drug (including benzodiazepines \[BZD\]) dependence (DSM IV criteria) within 1 year of the study and lasting longer than 2 years, except for alcohol dependence;
4. . current pregnancy (as documented by pregnancy testing at screening or on the day of PET imaging study);
5. . current breast feeding;
6. . nicotine dependence;
7. . suicidal ideation or behavior;
9. . HIV (due to possible neuropsychiatric effects);
10. . Hepatitis B or C (due to possible neuropsychiatric effects);
11. . use of opioid medications within 2 weeks of the PET study;
12. . having an abnormality in the 12-lead ECG that, in the opinion of the investigator, increases the risks associated with participation in the study;
13. . seriously claustrophobic;
14. . blood donation within 8 weeks prior to the study;
15. . positive alcohol breathalyzer test;
16. . Abnormal thyroid test indicated by TSH \< .15 mlU/L and/or T4 \> 18 mcg/dL;
17. . Glucose \> 200 mg/dL on two separate days;
18. . Does not have a lifetime history of trauma.
For Healthy Subjects with Trauma ("Trauma Controls")
1. . any history or current primary Axis I disorder ;
2. . medical or neurological illnesses likely to affect physiology or anatomy, i.e. uncontrolled hypertension, cardiovascular disorders;
3. . a history of drug (including benzodiazepines \[BZD\]) dependence (DSM IV criteria) within 1 year of the study and lasting longer than 2 years, except for alcohol dependence;
4. . current pregnancy (as documented by pregnancy testing at screening or on the day of PET imaging study);
5. . current breast feeding;
6. . nicotine dependence;
7. . suicidal ideation or behavior;
9. . HIV (due to possible neuropsychiatric effects);
10. . Hepatitis B or C (due to possible neuropsychiatric effects);
11. . use of opioid medications within 2 weeks of the PET study;
12. . having an abnormality in the 12-lead ECG that, in the opinion of the investigator, increases the risks associated with participation in the study;
13. . seriously claustrophobic;
14. . blood donation within 8 weeks prior to the study;
15. . positive alcohol breathalyzer test;
16. . Abnormal thyroid test indicated by TSH \< .15 mlU/L and/or T4 \> 18 mcg/dL;
