Lead Sponsor

University of Dundee

Collaborators

Age

16 - No limit years

Sex

ALL

Healthy Volunteers

No

•Male or female volunteers aged at least 16 years with persistent asthma and on inhaled corticosteroids (at least 400 micrograms of beclomethasone dipropionate or the equivalent
•FEV1 \> 50 % predicted
•Mannitol PD15 \< 635 mg
•Ability to give informed consent
•Agreement for their general practitioner to be made aware of study participation and to receive feedback as relevant to the participant's well being

•Other respiratory diseases such as chronic obstructive pulmonary disease, bronchiectasis or allergic bronchopulmonary aspergillosis
•An asthma exacerbation or respiratory tract infection requiring systemic steroids and/or antibiotics within 3 months of the study commencement
•Any clinically significant medical condition that may endanger the health or safety of the participant
•Smoking within one year or \>10 pack year history
•Participation in another trial within 30 days before the commencement of the study
•Pregnancy or lactation
•Unable to comply with the procedures of the protocol