Average DBP measured by 24-hour ambulatory blood pressure monitoring (ABPM) ≥80 mmHg
You may not be if
Secondary hypertension and malignant hypertension
Pregnant or nursing women, or patients that cannot guarantee to take effective contraception measures
Baseline SBP≥180 mmHg or DBP≥110 mmHg, or patients with cerebral, cardiac or renal complications
Have following complications: cerebrovascular accident within 6 months, myocardial infarction or cardiac failure, macroaneurysm or dissecting aneurysm, definite angina, A-V block of grade 2 or higher, sick sinus syndrome, atrial fibrillation or other malignant arrhythmia
Clinical significant diseases of heart, lung, liver, kidney and hematologic system or malignant tumors, HIV infection, uncontrolled diabetes (fasting blood glucose ≥7.0 mmol/L, 2-hour postprandial blood glucose ≥7.8 mmol/L)
Kock pouch
Sever gastrointestinal stenosis
Abnormal laboratory values with clinical significance, including serum potassium \<3.5 or \>5.5 mmol/L, glutamic-pyruvic transaminase (ALT) or glutamic oxalacetic transaminase (AST) \>2-fold upper limit of normal (ULN), Cr \>ULN
Uric acid \>ULN with the diagnosis of gout
Gastrointestinal abnormalities or surgery that may interfere with drug absorption
Hyperthyroidism or hypothyroidism
Allergic to any ingredient or metabolite of investigational drug or drugs of similar structure
Heavy smokers (\>25 cigarettes every day), alcoholics (\>250 ml liquor every day), drug addicts
