Although stageⅠ-ⅢA, have contraindications to surgery;
EGFR mutation-positive (EGFR exon-18, exon-19 or exon-21);
Measurable disease;
ECOG Performance Status 0 or 1 or 2.
You may not be if
Wild-type EGFR;
Prior exposure to agents directed at the HER axis;
Prior chemotherapy or systemic anti-tumor therapy after advanced disease;
Unstable systemic disease;
Any other malignancy within last 5 years, except cured basal cell cancer of skin or cured cancer in situ of cervix;
Brain metastasis or spinal cord compression.
Clareo Health | Intercalated Combination of Chemotherapy and Tyrosine Kinase Inhibitors as First-line Treatment for Patients With Non-Small-Cell Lung Cancer