Effect of Milk Ingredients on Glucose Regulation and Inflammation

Exclusion Criteria

• •Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study
• •Participation in any non-invasive clinical trial up to 30 days before Day 01 of this study, including no blood sampling and/or oral, intravenous or inhalatory administration of substances
• •Having a history of medical or surgical events that may significantly affect the study outcome, including: Inflammatory bowel disease, ulcers, gastrointestinal or rectal bleeding; major gastrointestinal tract surgery such as gastrectomy, gastroenterostomy, or bowel resection; known or suspected gastrointestinal strictures
• •Medical drug use; antibiotics, laxatives, glucose lowering drugs, insulin; all medication with an inflammation inhibiting effect (e.g. NSAIDS, corticosteroids) and/or an effect on blood coagulation (e.g. coumarins, inhibitors of thrombin or factor Xa, acetylsalicylic acid, antidepressants from the group of serotonin reabsorption inhibitors, tranexamin acid)
• •Mental status that is incompatible with the proper conduct of the study
• •A self-reported reported food allergy or sensitivity (wheat, milk, lactose, eggs, nuts, etc)
• •Alcohol consumption \> 28 units/week and 4/day
• •Exercise \> 3 hours/week
• •Smoking \>20 cigarettes/day
• •Reported unexplained weight loss or weight gain of \> 3 kg in the month prior to pre-study screening
• •Reported slimming or medically prescribed diet
• •Reported vegan or macrobiotic life-style
• •Recent blood donation (\<1 month prior to Day 01 of the study)
• •Not willing or afraid to give up blood donation during the study
• •Personnel of NIZO food research or Wageningen University, department of Human Nutrition, their partner and their first and second degree relatives
• •Not having a general practitioner
• •Not willing to accept information-transfer concerning participation in the study, or information regarding his health, like laboratory results, findings at anamnesis or physical examination and eventual adverse events to and from his general practitioner