Cryoablation of Small Breast Tumors in Early Stage Breast Cancer

Inclusion Criteria

• •1. Age ≥ 50
• •2. Unifocal primary invasive breast carcinoma diagnosed by core needle biopsy
• •3. Maximum tumor size ≤1.5 cm in its greatest diameter
• •4. Ultrasound visible lesion(s)
• •5. Clinically node negative, hormone receptor positive (+). HER2 negative (-), with \<25% intraductal component in the aggregate.
• •6. Unilateral or bilateral disease meeting study criteria
• •7. Physical and emotional ability to undergo baseline and follow-up breast MRIs and serial breast cosmesis analysis
• •8. Patient agrees to receive a 5 year minimum course of endocrine therapy following cryoablation for control of systemic disease