Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Stichting Epilepsie Instellingen Nederland
With
Fonds NutsOhra
Medtronic
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Drug-resistant focal epilepsy: failure of adequate trials of two tolerated and appropriately chosen and used antiepileptic drug (AED) schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom \[16\]
≥ 1 complex partial and/or generalized tonic clonic seizure/month as indicated by history taking
If female, not pregnant
Aged 18 to 60 years
Able to undergo the study procedure as judged by the treating physician.
You may not be if
Clinical suspicion of seizure-induced asystole (e.g. seizures with sudden flaccid falls)
Reveal implantation (either present or in the past)
Known clinical relevant structural cardiac disease
Hereditary syndromes that increase the risk of cardiomyopathy (e.g. Marfan's disease)
ECG findings suggestive of arrhythmias without proper cardiac evaluation to in- or exclude this possibility. According to European Society of Cardiology (ESC) guidelines on syncope the following ECG findings will be used: bifascicular block and other intraventricular conduction abnormalities, asymptomatic inappropriate sinus bradycardia (\<50 bpm), sinoatrial block or sinus pause ≥3s in the absence of negative chronotropic medications, non-sustained VT, pre-exited QRS complexes, prolonged or short QT interval, Brugada pattern, pattern suggestive of arrhythmogenic right ventricular cardiomyopathy.
Pacemaker
Use of beta blockers or other anti-arrhythmic/anti-arrhythmogenic medication
Previous diagnosis of psychogenic non-epileptic seizures
Patients who live alone and are not able to recall their seizures
Clareo Health | Cardiac Arrhythmias in Epilepsy: the CARELINK-study
