Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sunnybrook Health Sciences Centre
With
The Depressive and Bipolar Disorder Alternative Treatment Foundation
Age
13–19
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
English speaking
all races and ethnicities
bipolar disorder I or II
currently treated with lithium, divalproex, lamotrigine, and/or second generation antipsychotic
doses stable for greater than or equal to 4 weeks
current CGI BP score of moderate or greater
current CDRS-R severity of greater than or equal to 35
You may not be if
If female, pregnant or sexually active without reliable contraception
significant suicidal ideations (as determined by clinical interview or CDRS-R \> 3) and/or any suicidal intent, even if fleeting or non-recurrent, in the preceding 2 weeks
substance dependence within the past 2 months
daily antidepressant, glucocorticoid, nonsteroidal anti-inflammatory, anti-platelet, anti-coagulant, antacid, or oral hypoglycemic medication or insulin; high-dose antioxidant vitamin supplements or other natural health products that may function as an antidepressant within 30 days of baseline
IQ\<80 or autistic disorder
full threshold mania and/or YMRS \> 20 and/or psychosis
hypersensitivity to curcumin/turmeric, gelatin
dietary consumption of curcumin/turmeric \> 3 times/week
clinically significant or unstable medical disorder; known gallstones and/or bile duct obstruction, stomach ulcers, excessive stomach acid/heartburn/gastroesophageal reflux disease (GERD); or clinically significant baseline laboratory abnormalities; or ALT and /or AST above the upper limit of normal on repeat examination at baseline
severe depression (CDRS-R \> 98) and/or severely ill (CGI BP \>5)
Clareo Health | Adjunctive Curcumin for Symptomatic Adolescents With Bipolar Disorder: Brain and Body Considerations
