Mild TBI: PTA/confusion≤1 hour immediately after injury; or LOC \<30 min \[69\] confirmed by the Ohio confirmed by the Ohio State University TBI Identification Method-Short Form (OSU TBI-ID-SF).
Age 18-45 years
Right handed \[70\].
Minimum of 4 months and within 36 months post-injury
Can participate in fMRI and outcome assessment
Adequate visual, auditory, sensory-motor function for training program.
Fluent in English
Persistent cognitive dysfunction confirmed by an objective measure
Contraindications to MRI (metal, pregnant, pacemaker, claustrophobia, etc.).
Unwilling or unable (e.g. language barrier) to participate
Hospitalization during study
Current Med Board for discharge, Litigation/ + malingering test \[71\]
Use of medications to enhance cognitive function (e.g. Ritalin)
Initial Glascow Coma Score \<13 or penetrating head injury
Subjects must not show suicidal ideation as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS; 111). Subjects with a score of 4 or 5 (as recommended by the FDA for treatment trials) will be excluded and referred for appropriate treatment.
Subjects should not be enrolled in a concurrent TBI clinical trial.
