Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment

Exclusion Criteria

• •Ongoing use of a potassium sparing diuretic
• •History of congestive heart failure (ejection fraction of \<40%)
• •Chronic kidney disease (creatinine clearance \<60 ml/min)
• •History of cardiovascular disease (stroke, TIA, myocardial infarction, or revascularization procedure)
• •Known or suspected history of secondary cause of hypertension other than primary aldosteronism
• •Severe nocturnal hypoxemia (O2 desaturation nadir \<60%)
• •White coat hypertension defined as office BP \>140/90 mm Hg and ambulatory daytime BP \<135/85 mm Hg
• •Central sleep apnea (defined as 5% or more of the apneas as central apneas) and/or the presence of any Cheyne-Stokes breathing
• •Subjects working shift work or having other known circadian rhythm disorders such that their sleep-wake schedule is altered
• •Excessive daytime sleepiness as indicated by an Epworth score of \>10
• •Pregnant Women