Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging

Inclusion Criteria

• •Healthy controls
• •Men and women aged over 18 years
• •Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• •Normal ophthalmic findings
• •Patients with ocular hypertension
• •Men and women aged over 18 years
• •Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• •Normal ophthalmic findings except presence of ocular hypertension (defined as untreated IOP ≥ 21 mmHg on at least three measurements in the medical history, no signs of glaucomatous damage in the optic disc or the glaucoma hemifield test)
• •Patients with primary open angle glaucoma
• •Men and women aged over 18 years
• •Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• •Diagnosis of manifest primary open angle glaucoma (defined as pathological optic disc appearance, glaucoma hemifield test outside normal limits and untreated IOP \> 20 mmHg on at least three measurements in the medical history)
• •Mean Deviation in the visual field test ≥ 10dB
• •Patients with normal-tension glaucoma
• •Men and women aged over 18 years
• •Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• •Diagnosis of normal-tension glaucoma (defined as pathological optic disc appearance, glaucoma hemifield test outside normal limits and untreated IOP ≤ 20 mmHg on at least three measurements in the medical history)
• •Mean Deviation in the visual field test ≥ 10dB